Omics Sciences in Biological Systems and Human Diseases
This research line focuses on molecular-level investigations, including studies in bioinformatics, molecular biology, biochemistry, genetics, epigenetics, biophotonics, metagenomics, proteomics, and transcriptomics. It prioritizes human diseases of genetic origin, microorganism-induced diseases, and the role of natural compounds (including foods and their derivatives) in health and disease at the molecular level. Main themes include:
(I) Genetic diseases and determinants in humans, their interactions, phenotypic impact, and epigenetic modulation;
(II) Computational biochemistry and biophysics focused on neurodegenerative diseases, psychiatric disorders, and rational drug design;
(III) Safety and toxicity of bioactive compounds using experimental and computational models;
(IV) Host-pathogen interaction and expression of recombinant proteins using high-throughput systems;
(V) Molecular and cellular effects of non-ionizing radiation;
(VI) Proteomic and metabolomic analysis of bioactive compounds applied to organisms of biotechnological and environmental interest;
(VII) Food science and technology focusing on composition, bioavailability, and bioactivity in vivo and in vitro models;
(VIII) Precision medicine and nutrition.
Associated projects:
- Omic approaches to study the functionality of proteins and bioactive compounds from sorghum and wheat
- Analysis of genetic factors involved in the development of neurodegenerative diseases during aging
- Evaluation of natural and synthetic compounds
- Epigenetics and gene expression related to DNA repair pathways, tumor hypoxia, and resistance phenotypes in cancer cells
- Genomics and diagnosis of enterobacteria
- Molecular and epidemiological investigation of genetic diseases
- Structural protein modeling and drug design